Tetrahydrofuran (THF) is a colorless organic liquid that is miscible with water and has a low viscosity at normal temperature and pressure. The chemical formula of this cyclic ether can be written as (CH2) 4O. Because of its long liquid range, it is a commonly used medium-polar aprotic solvent. Its main use is as a precursor of high molecular polymers. Although the smell and chemical properties of THF are very similar to ether, the anesthetic effect is very poor.
Product Name:Tetrahydrofuran（THF）
Cas:109-99-9
Purity：99.9%min
Package：180Kg/Drum or Isotank
Application:Synthesis of Ptmeg, pharmaceutical & pesticide intermediates,chromatographic solvent.
Place of Origin:China(Mainland)
Port of Loading:Shanghai or Qingdao
Terms of Payment: TT、LC、DP
Delivery time: In stock
Tetrahydrofuran (THF) functions and uses:
1. Used as a raw material for solvents and organic synthesis.
2. Used as chromatographic analysis reagent, organic solvent and nylon 66 intermediate. Tetrahydrofuran, also known as monooxa, oxacyclopentane, and tetramethylene oxide, is an intermediate in the synthesis of pesticide styrene butadiene. In addition, it can be directly used in the production of synthetic fibers, synthetic resins, synthetic rubber, and many polymeric materials. , Precision tapes and solvents for the electroplating industry. It is also used to make adiponitrile, adipic acid, hexamethylene diamine, succinic acid, butanediol, γ-butyrolactone, etc. In the pharmaceutical industry, it can be used to produce cough clear, Progesterone, rifamycin and used as pharmaceutical solvents.
3. Tetrahydrofuran is an important organic synthetic raw material and a solvent with excellent performance. It is particularly suitable for dissolving PVC, polyvinylidene chloride and butyl aniline. It is widely used as a solvent for surface coatings, anticorrosive coatings, printing inks, magnetic tapes and film coatings. , And used as a reaction solvent, the thickness of the aluminum layer can be arbitrarily controlled and bright when used in electroplating aluminum liquid. Tetrahydrofuran itself can be polycondensed (by cation-induced ring-opening repolymerization) to form polytetramethylene ether glycol (PTMEG), also known as tetrahydrofuran homopolyether. PTMEG and toluene diisocyanate (TDI) are made into special rubbers with wear resistance, oil resistance, low temperature performance and high strength; and block polyether polyester elasticity with dimethyl terephthalate and 1,4-butanediol material. PTMEG with a relative molecular weight of 2000 and p-methylene bis (4-phenyl) diisocyanate (MDI) are used as raw materials for polyurethane elastic fibers (spandex, or SPANDEX fibers), special rubbers, and some special-purpose coatings. In organic synthesis, it is used to produce tetrahydrothiophene, 1.2-dichloroethane, 2.3-dichlorotetrahydrofuran, valerolactone, butyrolactone and pyrrolidone. In the pharmaceutical industry, THF is used to synthesize cetrine, rifamycin, progesterone and some hormone drugs. THF is treated with hydrogen sulfide to produce tetrahydrothiophenol, which can be used as odorant (identification additive) in fuel gas. THF can also be used as a surface treatment agent for synthetic leather.
Precautions for using tetrahydrofuran (THF):
Respiratory protection: When it may be exposed to its vapor, it should wear a filter gas mask (half mask). When necessary, it is recommended to wear self-contained breathing apparatus.
Eye protection: Generally no special protection is required, and safety protective glasses can be worn when exposed to high concentrations.
Body protection: Wear anti-static overalls.
Hand protection: Wear anti-benzene oil resistant gloves.
Others: Smoking is strictly prohibited at the work site. After work, take a shower and change clothes. Pay attention to personal hygiene.
Skin contact: Remove contaminated clothing and wash skin thoroughly with soap and water.
Eye contact: Lift the eyelid and rinse with running water or saline. See a doctor.
Inhalation: Quickly leave the scene to fresh air. Keep the airway clear. If breathing is difficult, give oxygen. If breathing stops, give artificial respiration immediately. See a doctor.
Ingestion: Drink plenty of warm water, induce vomiting, and seek medical attention.
Fire extinguishing method: Use water spray to cool the container. If possible, move the container from the fire to an open place. If the container in the fire scene has changed color or produces sound from the safety pressure relief device, it must be evacuated immediately.
Extinguishing agent: foam, dry powder, carbon dioxide, sand. Fire extinguishing is invalid.
Small amount of leakage: use sand or other non-combustible materials to absorb or absorb. It can also be rinsed with a large amount of water, diluted with washing water and put into the waste water system.
Large amount of leakage: constructing dikes or digging pits to contain. Cover with foam to reduce steam hazards. Spray water to cool and dilute the steam, protect the personnel on site, and dilute the leakage into non-combustibles. Use an explosion-proof pump to transfer to tank truck or special collector, and recycle or transport to waste disposal site for disposal.
Notes on operation: airtight operation and full ventilation. Operators must undergo special training and strictly abide by the operating regulations. It is recommended that operators wear filter gas masks (half masks), safety glasses, anti-static overalls, and rubber oil-resistant gloves. Keep away from fire and heat, smoking is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment. Prevent vapor from leaking into the workplace air. Avoid contact with oxidants, acids and alkalis. The flow rate should be controlled during filling, and there should be a grounding device to prevent the accumulation of static electricity. Handle lightly when handling to prevent damage to packaging and containers. Equipped with corresponding varieties and quantities of fire fighting equipment and leakage emergency treatment equipment. Empty containers may be harmful residues.
Precautions for storage: Usually the product is added with polymerization inhibitor. Store in a cool, ventilated warehouse. Keep away from fire and heat. The storage temperature should not exceed 30 ℃. The packaging needs to be sealed and not in contact with air. It should be stored separately from oxidants, acids, alkalis, etc., and avoid mixed storage. Use explosion-proof lighting and ventilation facilities. It is forbidden to use mechanical equipment and tools that easily generate sparks. The storage area should be equipped with leakage emergency treatment equipment and suitable containment materials.
Vocational standards: TWA 590 mg / m3; STEL 640 mg / m3 [5]